| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:6000 IHC-P:1:100-1:500 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HES5 |
| Gene ID: | 388585 |
| Uniprot ID: | HES5_HUMAN |
| Immunogen Region: | 12-142 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 12-142 of human HES5 (Q5TA89). |
| Immunogen Sequence: | SPKEKNRLRKPVVEKMRRDR INSSIEQLKLLLEQEFARHQ PNSKLEKADILEMAVSYLKH SKAFVAAAGPKSLHQDYSEG YSWCLQEAVQFLTLHAASDT QMKLLYHFQRPPAAPAAPAK EPKAPGAAPPP |
| Tissue Specificity | Expressed in fetal heart and brain tumors. |
| Function | Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator. |
| Protein Name | Transcription Factor Hes-5 Class B Basic Helix-Loop-Helix Protein 38 Bhlhb38 Hairy And Enhancer Of Split 5 |
| Database Links | Reactome: R-HSA-2122947 Reactome: R-HSA-2197563 Reactome: R-HSA-2644606 Reactome: R-HSA-2894862 Reactome: R-HSA-9013508 Reactome: R-HSA-9013695 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Hes-5 antibody Anti-Class B Basic Helix-Loop-Helix Protein 38 antibody Anti-Bhlhb38 antibody Anti-Hairy And Enhancer Of Split 5 antibody Anti-HES5 antibody Anti-BHLHB38 antibody |
Information sourced from Uniprot.org