Anti-HES5 antibody (12-142) [S4MR] (STJ11102544)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal HES5 (12-142) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:6000IHC-P:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HES5 |
| Gene ID | 388585 |
| Uniprot ID | HES5_HUMAN |
| Immunogen Region | 12-142 |
| Immunogen Sequence | SPKEKNRLRKPVVEKMRRDR INSSIEQLKLLLEQEFARHQ PNSKLEKADILEMAVSYLKH SKAFVAAAGPKSLHQDYSEG YSWCLQEAVQFLTLHAASDT QMKLLYHFQRPPAAPAAPAK EPKAPGAAPPP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 12-142 of human HES5 (Q5TA89). |
Additional Info
| Tissue Specificity | Expressed in fetal heart and brain tumors. |
| Function | Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator. |
| Protein Name | Transcription Factor Hes-5Class B Basic Helix-Loop-Helix Protein 38Bhlhb38Hairy And Enhancer Of Split 5 |
| Database Links | Reactome: R-HSA-2122947Reactome: R-HSA-2197563Reactome: R-HSA-2644606Reactome: R-HSA-2894862Reactome: R-HSA-9013508Reactome: R-HSA-9013695 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Hes-5 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 38 antibodyAnti-Bhlhb38 antibodyAnti-Hairy And Enhancer Of Split 5 antibodyAnti-HES5 antibodyAnti-BHLHB38 antibody |
Information sourced from Uniprot.org