Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-HEPACAM (35-245) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HEPACAM |
Gene ID: |
220296 |
Uniprot ID: |
HECAM_HUMAN |
Immunogen Region: |
35-245 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 35-245 of human HEPACAM (NP_689935.2). |
Immunogen Sequence: |
NITSPVRLIHGTVGKSALLS VQYSSTSSDRPVVKWQLKRD KPVTVVQSIGTEVIGTLRPD YRDRIRLFENGSLLLSDLQL ADEGTYEVEISITDDTFTGE KTINLTVDVPISRPQVLVAS TTVLELSEAFTLNCSHENGT KPSYTWLKDGKPLLNDSRML LSPDQKVLTITRVLMEDDDL YSCMVENPISQGRSLPVKIT VYRRSSLYIIL |
Post Translational Modifications | N-glycosylated. |
Function | Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. |
Protein Name | Hepatic And Glial Cell Adhesion MoleculeGlialcamHepatocyte Cell Adhesion MoleculeProtein Hepacam |
Cellular Localisation | CytoplasmMembraneSingle-Pass Type I Membrane ProteinCytoplasmic SideIn Mcf-7 Breast Carcinoma And Hepatic Hep 3b21-7 And Hep-G2 Cell LinesLocalization Of Hepacam Is Cell Density-DependentIn Well Spread CellsLocalized To Punctate Structures In The Perinuclear MembraneAnd At Cell Surface Of ProtusionsIn Confluent CellsLocalized Predominantly To The Cytoplasmic MembraneParticularly In Areas Of Cell-Cell ContactsColocalizes With Cdh1 |
Alternative Antibody Names | Anti-Hepatic And Glial Cell Adhesion Molecule antibodyAnti-Glialcam antibodyAnti-Hepatocyte Cell Adhesion Molecule antibodyAnti-Protein Hepacam antibodyAnti-HEPACAM antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance