Anti-Hemopexin antibody (Internal) (STJ73799)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Hemopexin (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 80kDa band observed in Human Liver and Placenta lysates (calculated MW of 51.7kDa according to NP_000604.1). The observed molecular weight corresponds to the glycosylated form. R |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | HPX |
| Gene ID | 3263 |
| Uniprot ID | HEMO_HUMAN |
| Accession Number | NP_000604.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | HGNVAEGETKPDPD |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29. |
| Function | Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. |
| Protein Name | HemopexinBeta-1b-Glycoprotein |
| Database Links | Reactome: R-HSA-2168880 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Hemopexin antibodyAnti-Beta-1b-Glycoprotein antibodyAnti-HPX antibody |
Information sourced from Uniprot.org