Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-Hemopexin (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 80kDa band observed in Human Liver and Placenta lysates (calculated MW of 51.7kDa according to NP_000604.1). The observed molecular weight corresponds to the glycosylated form. R |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
HPX |
Gene ID: |
3263 |
Uniprot ID: |
HEMO_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_000604.1 |
Immunogen Sequence: |
HGNVAEGETKPDPD |
Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29. |
Function | Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. |
Protein Name | HemopexinBeta-1b-Glycoprotein |
Database Links | Reactome: R-HSA-2168880 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Hemopexin antibodyAnti-Beta-1b-Glycoprotein antibodyAnti-HPX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance