| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Hemopexin (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 80kDa band observed in Human Liver and Placenta lysates (calculated MW of 51.7kDa according to NP_000604.1). The observed molecular weight corresponds to the glycosylated form. R |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HPX |
| Gene ID: | 3263 |
| Uniprot ID: | HEMO_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000604.1 |
| Immunogen Sequence: | HGNVAEGETKPDPD |
| Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29. |
| Function | Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. |
| Protein Name | HemopexinBeta-1b-Glycoprotein |
| Database Links | Reactome: R-HSA-2168880 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Hemopexin antibodyAnti-Beta-1b-Glycoprotein antibodyAnti-HPX antibody |
Information sourced from Uniprot.org