Anti-HELLS antibody (STJA0007143)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human HELLS
General Information
| Short Description | Rabbit polyclonal anti-Lymphoid-specific helicase for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HELLS |
| Gene ID | 3070 |
| Uniprot ID | HELLS_HUMAN |
| Immunogen | Synthesized peptide derived from human HELLS |
| Specificity | This antibody detects endogenous levels of HELLS at Human, Mouse |
Additional Info
| Function | Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis. |
| Protein Name | Lymphoid-Specific HelicaseProliferation-Associated Snf2-Like ProteinSwi/Snf2-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 6 |
| Database Links | Reactome: R-HSA-9839394 |
| Cellular Localisation | NucleusClosely Associated With Pericentric Heterochromatin |
| Alternative Antibody Names | Anti-Lymphoid-Specific Helicase antibodyAnti-Proliferation-Associated Snf2-Like Protein antibodyAnti-Swi/Snf2-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 6 antibodyAnti-HELLS antibodyAnti-PASG antibodyAnti-SMARCA6 antibodyAnti-Nbla10143 antibody |
Information sourced from Uniprot.org