Anti-HCN4 antibody (600-680 aa) (STJ191195)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 600-680
General Information
| Short Description | Rabbit polyclonal anti-Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (600-680 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HCN4 |
| Gene ID | 10021 |
| Uniprot ID | HCN4_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 600-680 |
| Immunogen Region | 600-680 aa |
| Specificity | HCN4 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | S-palmitoylated. |
| Function | Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation. Exhibits higher selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli. |
| Protein Name | Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 4 |
| Database Links | Reactome: R-HSA-1296061 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 4 antibodyAnti-HCN4 antibody |
Information sourced from Uniprot.org