• Immunofluorescence analysis of NIH/3T3 cells using HCN1 Rabbit polyclonal antibody (STJ118638) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates, using HCN1 antibody (STJ118638) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-HCN1 antibody (791-890) (STJ118638)

SKU:
STJ118638

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-HCN1 (791-890) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HCN1
Gene ID: 348980
Uniprot ID: HCN1_HUMAN
Immunogen Region: 791-890
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 791-890 of human HCN1 (NP_066550.2).
Immunogen Sequence: PSLPHEVSTLISRPHPTVGE SLASIPQPVTAVPGTGLQAG GRSTVPQRVTLFRQMSSGAI PPNRGVPPAPPPPAAALPRE SSSVLNTDPDAEKPRFASNL
Tissue Specificity Detected in brain, in particular in amygdala and hippocampus, while expression in caudate nucleus, corpus callosum, substantia nigra, subthalamic nucleus and thalamus is very low or not detectable. Detected at very low levels in muscle and pancreas.
Function Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). May mediate responses to sour stimuli.
Protein Name Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 1
Brain Cyclic Nucleotide-Gated Channel 1
Bcng-1
Database Links Reactome: R-HSA-1296061
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 1 antibody
Anti-Brain Cyclic Nucleotide-Gated Channel 1 antibody
Anti-Bcng-1 antibody
Anti-HCN1 antibody
Anti-BCNG1 antibody

Information sourced from Uniprot.org

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