| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HUWE1-associated protein modifying stress responses 1 (55-105 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HAPSTR1 |
| Gene ID: |
29035 |
| Uniprot ID: |
HAPR1_HUMAN |
| Immunogen Region: |
55-105 aa |
| Specificity: |
This antibody detects endogenous levels of CP072 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human CP072 at the amino acid range 55-105 |
| Function | Acts as a central player within a network of stress response pathways promoting cellular adaptability. The E3 ligase HUWE1 assists HAPSTR1 in controlling stress signaling and in turn, HUWE1 feeds back to promote the degradation of HAPSTR1. HAPSTR1 represents a central coordination mechanism for stress response programs. Functions as a negative regulator of TP53/P53 in the cellular response to telomere erosion and probably also DNA damage. May attenuate p53/TP53 activation through the E3 ubiquitin ligase HUWE1. |
| Protein Name | Huwe1-Associated Protein Modifying Stress Responses 1Telomere Attrition And P53 Response 1 Protein |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Huwe1-Associated Protein Modifying Stress Responses 1 antibodyAnti-Telomere Attrition And P53 Response 1 Protein antibodyAnti-HAPSTR1 antibodyAnti-C16orf72 antibodyAnti-TAPR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
