Anti-H2AC21 antibody (15-65 aa) (STJ195952)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human H2A2B at the amino acid range 15-65
General Information
| Short Description | Rabbit polyclonal anti-Histone H2A type 2-B (15-65 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | H2AC21 |
| Gene ID | 317772 |
| Uniprot ID | H2A2B_HUMAN |
| Immunogen | Synthesized peptide derived from the human H2A2B at the amino acid range 15-65 |
| Immunogen Region | 15-65 aa |
| Specificity | This antibody detects endogenous levels of H2A2B at Human/Mouse |
Additional Info
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Histone H2a Type 2-BH2a-Clustered Histone 21 |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-3214847Reactome: R-HSA-3214858Reactome: R-HSA-5689603Reactome: R-HSA-5689880Reactome: R-HSA-5689901Reactome: R-HSA-9609690Reactome: R-HSA-9610379 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone H2a Type 2-B antibodyAnti-H2a-Clustered Histone 21 antibodyAnti-H2AC21 antibodyAnti-HIST2H2AB antibody |
Information sourced from Uniprot.org