• Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-H2AC21 antibody (15-65 aa) (STJ195952)

SKU:
STJ195952

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Histone H2A type 2-B (15-65 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: H2AC21
Gene ID: 317772
Uniprot ID: H2A2B_HUMAN
Immunogen Region: 15-65 aa
Specificity: This antibody detects endogenous levels of H2A2B at Human/Mouse
Immunogen: Synthesized peptide derived from the human H2A2B at the amino acid range 15-65
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Name Histone H2a Type 2-B
H2a-Clustered Histone 21
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-3214847
Reactome: R-HSA-3214858
Reactome: R-HSA-5689603
Reactome: R-HSA-5689880
Reactome: R-HSA-5689901
Reactome: R-HSA-9609690
Reactome: R-HSA-9610379
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Histone H2a Type 2-B antibody
Anti-H2a-Clustered Histone 21 antibody
Anti-H2AC21 antibody
Anti-HIST2H2AB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance