| Short Description : | Rabbit polyclonal anti-Histone H1.1 (49-99 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | H1-1 |
| Gene ID: | 3024 |
| Uniprot ID: | H11_HUMAN |
| Immunogen: | Synthesized peptide derived from the human H11 at the amino acid range 49-99 |
| Immunogen Region: | 49-99 aa |
| Specificity: | This antibody detects endogenous levels of H11 at Human/Mouse/Rat |
| Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Also acts as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. |
| Protein Name | Histone H1.1Histone H1a |
| Database Links | Reactome: R-HSA-140342Reactome: R-HSA-2559584 |
| Cellular Localisation | NucleusChromosomeMainly Localizes In Euchromatin |
| Alternative Antibody Names | Anti-Histone H1.1 antibodyAnti-Histone H1a antibodyAnti-H1-1 antibodyAnti-H1F1 antibodyAnti-HIST1H1A antibody |
Information sourced from Uniprot.org
