| Short Description : | Rabbit monoclonal Glycophorin C (49-128) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S7MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GYPC |
| Gene ID: | 2995 |
| Uniprot ID: | GLPC_HUMAN |
| Immunogen Region: | 49-128 |
| Immunogen Sequence: | METSTPTIMDIVVIAGVIAA VAIVLVSLLFVMLRYMYRHK GTYHTNEAKGTEFAESADAA LQGDPALQDAGDSSRKEYFI |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 49-128 of human Glycophorin C (GYPC) (P04921). |
| Tissue Specificity | Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed. |
| Post Translational Modifications | O-glycosylated with core 1 or possibly core 8 glycans. |
| Function | This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells. |
| Protein Name | Glycophorin-CGlycoconnectinGlycophorin-DGpdGlycoprotein BetaPas-2'Sialoglycoprotein DCd Antigen Cd236 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinLinked To The Membrane Via Band 41 |
| Alternative Antibody Names | Anti-Glycophorin-C antibodyAnti-Glycoconnectin antibodyAnti-Glycophorin-D antibodyAnti-Gpd antibodyAnti-Glycoprotein Beta antibodyAnti-Pas-2' antibodyAnti-Sialoglycoprotein D antibodyAnti-Cd Antigen Cd236 antibodyAnti-GYPC antibodyAnti-GLPC antibodyAnti-GPC antibody |
Information sourced from Uniprot.org
