• Western blot analysis of extracts of various cell lines, using GSC Rabbit monoclonal antibody (STJ11103157) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-GSC antibody (1-100) [S7MR] (STJ11103157)

SKU:
STJ11103157

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-GSC (1-100) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S7MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GSC
Gene ID: 145258
Uniprot ID: GSC_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GSC (P56915).
Immunogen Sequence: MPASMFSIDNILAARPRCKD SVLPVAHSAAAPVVFPALHG DSLYGASGGASSDYGAFYPR PVAPGGAGLPAAVSGSRLGY NNYFYGQLHVQAAPVGPACC
Function Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear.required for the development of the entire tympanic ring. Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals.
Protein Name Homeobox Protein Goosecoid
Database Links Reactome: R-HSA-9754189
Reactome: R-HSA-9823730
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Homeobox Protein Goosecoid antibody
Anti-GSC antibody

Information sourced from Uniprot.org

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