| Short Description : | Rabbit polyclonal GRPEL1 (1-217) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GRPEL1 |
| Gene ID: | 80273 |
| Uniprot ID: | GRPE1_HUMAN |
| Immunogen Region: | 1-217 |
| Immunogen Sequence: | MAAQCVRLARRSLPALALSL RPSPRLLCTATKQKNSGQNL EEDMGQSEQKADPPATEKTL LEEKVKLEEQLKETVEKYKR ALADTENLRQRSQKLVEEAK LYGIQAFCKDLLEVADVLEK ATQCVPKEEIKDDNPHLKNL YEGLVMTEVQIQKVFTKHGL LKLNPVGAKFDPYEHEALFH TPVEGKEPGTVALVSKVGYK LHGRTLRPALVGVVKEA |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GRPEL1 (NP_079472.1). |
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. |
| Protein Name | Grpe Protein Homolog 1 - MitochondrialHmgeMt-Grpe#1 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Grpe Protein Homolog 1 - Mitochondrial antibodyAnti-Hmge antibodyAnti-Mt-Grpe#1 antibodyAnti-GRPEL1 antibodyAnti-GREPEL1 antibody |
Information sourced from Uniprot.org
