Host: | Rabbit |
Applications: | WB/IHC-P/IF/ICC/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | GRPEL1 |
Gene ID: | 80273 |
Uniprot ID: | GRPE1_HUMAN |
Immunogen Region: | 1-217 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GRPEL1 (NP_079472.1). |
Immunogen Sequence: | MAAQCVRLARRSLPALALSL RPSPRLLCTATKQKNSGQNL EEDMGQSEQKADPPATEKTL LEEKVKLEEQLKETVEKYKR ALADTENLRQRSQKLVEEAK LYGIQAFCKDLLEVADVLEK ATQCVPKEEIKDDNPHLKNL YEGLVMTEVQIQKVFTKHGL LKLNPVGAKFDPYEHEALFH TPVEGKEPGTVALVSKVGYK LHGRTLRPALVGVVKEA |
Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. |
Protein Name | Grpe Protein Homolog 1 - MitochondrialHmgeMt-Grpe#1 |
Database Links | Reactome: R-HSA-1268020 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-Grpe Protein Homolog 1 - Mitochondrial antibodyAnti-Hmge antibodyAnti-Mt-Grpe#1 antibodyAnti-GRPEL1 antibodyAnti-GREPEL1 antibody |
Information sourced from Uniprot.org