Anti-GRM7 antibody (STJA0003689)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic phospho-peptide corresponding to amino acid residues surrounding Ser862 conjugated to KLH.
General Information
| Short Description | Rabbit polyclonal anti-mGluR7 for use in WB in Mouse, Rat, Bovine, Canine, Human, Non-Human Primates and Zebrafish samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat/Bovine/Canine/Human/Non-Human Primates/Zebrafish |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | This antibody was antigen affinity purified from serum. |
| Dilution Range | WB 1:1000 |
| Formulation | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Grm7 |
| Gene ID | 81672 |
| Uniprot ID | GRM7_RAT |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser862 conjugated to KLH. |
Additional Info
| Tissue Specificity | Widely distributed throughout the brain. |
| Function | G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits. |
| Protein Name | Metabotropic Glutamate Receptor 7Mglur7 |
| Database Links | Reactome: R-RNO-418594Reactome: -RNO-420499 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Metabotropic Glutamate Receptor 7 antibodyAnti-Mglur7 antibodyAnti-Grm7 antibodyAnti-Gprc1g antibodyAnti-Mglur7 antibody |
Information sourced from Uniprot.org