• Western blot analysis of lysates from mouse brain, using mGluR6 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using mGluR6 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-GRM6 antibody (828-877 aa) (STJ94111)

SKU:
STJ94111

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Metabotropic glutamate receptor 6 (828-877 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GRM6
Gene ID: 2916
Uniprot ID: GRM6_HUMAN
Immunogen Region: 828-877 aa
Specificity: mGluR-6 Polyclonal Antibody detects endogenous levels of mGluR-6 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human mGluR6 at the amino acid range 828-877
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.
Protein Name Metabotropic Glutamate Receptor 6
Mglur6
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-420499
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Endoplasmic Reticulum Membrane
Golgi Apparatus Membrane
Cell Projection
Dendrite
Subject To Trafficking From The Endoplasmic Reticulum To The Golgi Apparatus And Then To The Cell Membrane
Alternative Antibody Names Anti-Metabotropic Glutamate Receptor 6 antibody
Anti-Mglur6 antibody
Anti-GRM6 antibody
Anti-GPRC1F antibody
Anti-MGLUR6 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance