| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-mGluR2/3 (C-Term) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS + 0.02% NaN3 |
| Purification: |
Antigen Affinity Purified |
| Dilution Range: |
WB 1:500-1:1000IHC 1:5ICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GRM2 |
| Gene ID: |
2912 |
| Uniprot ID: |
GRM2_HUMAN |
| Immunogen Region: |
C-Term |
| Specificity: |
Reacts with the C-terminal region of human, mouse and rat mGlurR2/3 protein. |
| Immunogen: |
Synthetic peptide corresponding to amino acids from the C-terminal region of the human mGluR2/3 protein. |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. |
| Protein Name | Metabotropic Glutamate Receptor 2Mglur2 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-420499 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinSynapseCell ProjectionDendrite |
| Alternative Antibody Names | Anti-Metabotropic Glutamate Receptor 2 antibodyAnti-Mglur2 antibodyAnti-GRM2 antibodyAnti-GPRC1B antibodyAnti-MGLUR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
