| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Rhodopsin kinase GRK7 (371-420 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GRK7 |
| Gene ID: | 131890 |
| Uniprot ID: | GRK7_HUMAN |
| Immunogen Region: | 371-420 aa |
| Specificity: | GRK 7 Polyclonal Antibody detects endogenous levels of GRK 7 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GRK7 at the amino acid range 371-420 |
| Post Translational Modifications | Autophosphorylated in vitro at Ser-490. Phosphorylation at Ser-36 is regulated by light and activated by cAMP. |
| Function | Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). |
| Protein Name | Rhodopsin Kinase Grk7G Protein-Coupled Receptor Kinase 7G Protein-Coupled Receptor Kinase Grk7 |
| Database Links | Reactome: R-HSA-2514859 |
| Cellular Localisation | MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Rhodopsin Kinase Grk7 antibodyAnti-G Protein-Coupled Receptor Kinase 7 antibodyAnti-G Protein-Coupled Receptor Kinase Grk7 antibodyAnti-GRK7 antibodyAnti-GPRK7 antibody |
Information sourced from Uniprot.org