Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Gremlin-2 (71-120 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:500-200ELISA 1:10000-20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GREM2 |
Gene ID: |
64388 |
Uniprot ID: |
GREM2_HUMAN |
Immunogen Region: |
71-120 aa |
Specificity: |
The antibody detects endogenous Gremlin-2 |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the Internal region of human GREM2 at the amino acid range 71-120 |
Function | Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells. |
Protein Name | Gremlin-2Cysteine Knot Superfamily 1 - Bmp Antagonist 2Dan Domain Family Member 3Protein Related To Dan And Cerberus |
Database Links | Reactome: R-HSA-201451 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Gremlin-2 antibodyAnti-Cysteine Knot Superfamily 1 - Bmp Antagonist 2 antibodyAnti-Dan Domain Family Member 3 antibodyAnti-Protein Related To Dan And Cerberus antibodyAnti-GREM2 antibodyAnti-CKTSF1B2 antibodyAnti-DAND3 antibodyAnti-PRDC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance