• Immunofluorescence analysis of LOVO cells, using GPR75 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HT-29 and K562 cells, using GPR75 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of HT-29 cells using GPR75 Polyclonal Antibody

Anti-GPR75 antibody (381-430 aa) (STJ93395)

SKU:
STJ93395

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Probable G-protein coupled receptor 75 (381-430 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPR75
Gene ID: 10936
Uniprot ID: GPR75_HUMAN
Immunogen Region: 381-430 aa
Specificity: GPR75 Polyclonal Antibody detects endogenous levels of GPR75 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human GPR75 at the amino acid range 381-430
Function G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Protein Name Probable G-Protein Coupled Receptor 75
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Probable G-Protein Coupled Receptor 75 antibody
Anti-GPR75 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance