• Western blot analysis of Mouse thymus, using GPR68 Rabbit polyclonal antibody (STJ11104580) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-GPR68 antibody (276-365) (STJ11104580)

SKU:
STJ11104580

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ovarian Cancer G-Protein Coupled Receptor 1 (276-365) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPR68
Gene ID: 8111
Uniprot ID: OGR1_HUMAN
Immunogen Region: 276-365
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 276-365 of human GPR68 (NP_003476.3).
Immunogen Sequence: SFNCVADPVLYCFVSETTHR DLARLRGACLAFLTCSRTGR AREAYPLGAPEASGKSGAQG EEPELLTKLHPAFQTPNSPG SGGFPTGRLA
Tissue Specificity Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system.
Function Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also functions as a metastasis suppressor gene in prostate cancer.
Protein Name Ovarian Cancer G-Protein Coupled Receptor 1
Ogr-1
G-Protein Coupled Receptor 68
Gpr12a
Sphingosylphosphorylcholine Receptor
Database Links Reactome: R-HSA-373076
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Ovarian Cancer G-Protein Coupled Receptor 1 antibody
Anti-Ogr-1 antibody
Anti-G-Protein Coupled Receptor 68 antibody
Anti-Gpr12a antibody
Anti-Sphingosylphosphorylcholine Receptor antibody
Anti-GPR68 antibody
Anti-OGR1 antibody

Information sourced from Uniprot.org

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