| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Uracil nucleotide/cysteinyl leukotriene receptor (196-245 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR17 |
| Gene ID: | 2840 |
| Uniprot ID: | GPR17_HUMAN |
| Immunogen Region: | 196-245 aa |
| Specificity: | GPR17 Polyclonal Antibody detects endogenous levels of GPR17 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GPR17 at the amino acid range 196-245 |
| Function | Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. |
| Protein Name | Uracil Nucleotide/Cysteinyl Leukotriene ReceptorUdp/Cyslt ReceptorG-Protein Coupled Receptor 17P2y-Like ReceptorR12 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476Reactome: R-HSA-417957Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Uracil Nucleotide/Cysteinyl Leukotriene Receptor antibodyAnti-Udp/Cyslt Receptor antibodyAnti-G-Protein Coupled Receptor 17 antibodyAnti-P2y-Like Receptor antibodyAnti-R12 antibodyAnti-GPR17 antibody |
Information sourced from Uniprot.org
