| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Probable G-protein coupled receptor 132 (311-360 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR132 |
| Gene ID: | 29933 |
| Uniprot ID: | GP132_HUMAN |
| Immunogen Region: | 311-360 aa |
| Specificity: | GPR132 Polyclonal Antibody detects endogenous levels of GPR132 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GPR132 at the amino acid range 311-360 |
| Function | May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton-sensing activity. |
| Protein Name | Probable G-Protein Coupled Receptor 132 G2 Accumulation Protein |
| Database Links | Reactome: R-HSA-373076 Reactome: R-HSA-416476 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Internalized And Accumulated In Endosomal Compartments Lpc Triggers The Relocalization From The Endosomal Compartment To The Cell Surface |
| Alternative Antibody Names | Anti-Probable G-Protein Coupled Receptor 132 antibody Anti-G2 Accumulation Protein antibody Anti-GPR132 antibody Anti-G2A antibody |
Information sourced from Uniprot.org