| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-GPN-loop GTPase 1 (24-74 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPN1 |
| Gene ID: | 11321 |
| Uniprot ID: | GPN1_HUMAN |
| Immunogen Region: | 24-74 aa |
| Specificity: | This antibody detects endogenous levels of GPN1 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human GPN1 at the amino acid range 24-74 |
| Function | Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA. |
| Protein Name | Gpn-Loop Gtpase 1Mbd2-Interacting ProteinMbdinRnapii-Associated Protein 4Xpa-Binding Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Nucleus And The Cytoplasm |
| Alternative Antibody Names | Anti-Gpn-Loop Gtpase 1 antibodyAnti-Mbd2-Interacting Protein antibodyAnti-Mbdin antibodyAnti-Rnapii-Associated Protein 4 antibodyAnti-Xpa-Binding Protein 1 antibodyAnti-GPN1 antibodyAnti-MBDIN antibodyAnti-RPAP4 antibodyAnti-XAB1 antibodyAnti-HUSSY-23 antibody |
Information sourced from Uniprot.org
