Anti-GPI/Neuroleukin antibody (Internal) (STJ72087)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GPI/Neuroleukin (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 60kDa band observed in Human Heart lysates (calculated MW of 63.1kDa according to NP_000166.2). Recommended concentration: 0.01-0.03µg/ml. Primary incubation was hour.IHC: |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GPI |
| Gene ID | 2821 |
| Uniprot ID | G6PI_HUMAN |
| Accession Number | NP_000166.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | YREHRSELNLRR |
Additional Info
| Function | In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. |
| Protein Name | Glucose-6-Phosphate IsomeraseGpiAutocrine Motility FactorAmfNeuroleukinNlkPhosphoglucose IsomerasePgiPhosphohexose IsomerasePhiSperm Antigen 36Sa-36 |
| Database Links | Reactome: R-HSA-5628897Reactome: R-HSA-6798695Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | CytoplasmSecreted |
| Alternative Antibody Names | Anti-Glucose-6-Phosphate Isomerase antibodyAnti-Gpi antibodyAnti-Autocrine Motility Factor antibodyAnti-Amf antibodyAnti-Neuroleukin antibodyAnti-Nlk antibodyAnti-Phosphoglucose Isomerase antibodyAnti-Pgi antibodyAnti-Phosphohexose Isomerase antibodyAnti-Phi antibodyAnti-Sperm Antigen 36 antibodyAnti-Sa-36 antibodyAnti-GPI antibody |
Information sourced from Uniprot.org