Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Platelet Glycoprotein Ix (17-140) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | GP9 |
Gene ID: | 2815 |
Uniprot ID: | GPIX_HUMAN |
Immunogen Region: | 17-140 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-140 of human CD42a (NP_000165.1). |
Immunogen Sequence: | TKDCPSPCTCRALETMGLWV DCRGHGLTALPALPARTRHL LLANNSLQSVPPGAFDHLPQ LQTLDVTQNPWHCDCSLTYL RLWLEDRTPEALLQVRCASP SLAAHGPLGRLTGYQLGSCG WQLQ |
Function | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. |
Protein Name | Platelet Glycoprotein Ix Gp-Ix Gpix Glycoprotein 9 Cd Antigen Cd42a |
Database Links | Reactome: R-HSA-140837 Reactome: R-HSA-430116 Reactome: R-HSA-75892 Reactome: R-HSA-76009 Reactome: R-HSA-9673221 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Platelet Glycoprotein Ix antibody Anti-Gp-Ix antibody Anti-Gpix antibody Anti-Glycoprotein 9 antibody Anti-Cd Antigen Cd42a antibody Anti-GP9 antibody |
Information sourced from Uniprot.org