| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GOLM1 |
| Gene ID: | 51280 |
| Uniprot ID: | GOLM1_HUMAN |
| Immunogen Region: | 250-350 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human GOLPH2 (Q8NBJ4). |
| Immunogen Sequence: | VEKEETNEIQVVNEEPQRDR LPQEPGREQVVEDRPVGGRG FGGAGELGQTPQVQAALSVS QENPEMEGPERDQLVIPDGQ EEEQEAAGEGRNQQKLRGED D |
| Tissue Specificity | Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes. |
| Post Translational Modifications | Glycosylated. Phosphorylation sites are present in the extracellular medium. |
| Function | Unknown. Cellular response protein to viral infection. |
| Protein Name | Golgi Membrane Protein 1 Golgi Membrane Protein Gp73 Golgi Phosphoprotein 2 |
| Database Links | Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
| Cellular Localisation | Golgi Apparatus Cis-Golgi Network Membrane Single-Pass Type Ii Membrane Protein Early Golgi Cycles Via The Cell Surface And Endosomes Upon Lumenal Ph Disruption |
| Alternative Antibody Names | Anti-Golgi Membrane Protein 1 antibody Anti-Golgi Membrane Protein Gp73 antibody Anti-Golgi Phosphoprotein 2 antibody Anti-GOLM1 antibody Anti-C9orf155 antibody Anti-GOLPH2 antibody Anti-PSEC0242 antibody Anti-UNQ686 antibody Anti-PRO1326 antibody |
Information sourced from Uniprot.org