| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-GOLPH2 (250-350) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GOLM1 |
| Gene ID: |
51280 |
| Uniprot ID: |
GOLM1_HUMAN |
| Immunogen Region: |
250-350 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human GOLPH2 (Q8NBJ4). |
| Immunogen Sequence: |
VEKEETNEIQVVNEEPQRDR LPQEPGREQVVEDRPVGGRG FGGAGELGQTPQVQAALSVS QENPEMEGPERDQLVIPDGQ EEEQEAAGEGRNQQKLRGED D |
| Tissue Specificity | Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes. |
| Post Translational Modifications | Glycosylated. Phosphorylation sites are present in the extracellular medium. |
| Function | Unknown. Cellular response protein to viral infection. |
| Protein Name | Golgi Membrane Protein 1Golgi Membrane Protein Gp73Golgi Phosphoprotein 2 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Golgi ApparatusCis-Golgi Network MembraneSingle-Pass Type Ii Membrane ProteinEarly GolgiCycles Via The Cell Surface And Endosomes Upon Lumenal Ph Disruption |
| Alternative Antibody Names | Anti-Golgi Membrane Protein 1 antibodyAnti-Golgi Membrane Protein Gp73 antibodyAnti-Golgi Phosphoprotein 2 antibodyAnti-GOLM1 antibodyAnti-C9orf155 antibodyAnti-GOLPH2 antibodyAnti-PSEC0242 antibodyAnti-UNQ686 antibodyAnti-PRO1326 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
