Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-GNS (293-552) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GNS |
Gene ID: |
2799 |
Uniprot ID: |
GNS_HUMAN |
Immunogen Region: |
293-552 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 293-552 of human GNS (NP_002067.1). |
Immunogen Sequence: |
WQTLLSVDDLVEKLVKRLEF TGELNNTYIFYTSDNGYHTG QFSLPIDKRQLYEFDIKVPL LVRGPGIKPNQTSKMLVANI DLGPTILDIAGYDLNKTQMD GMSLLPILRGASNLTWRSDV LVEYQGEGRNVTDPTCPSLS PGVSQCFPDCVCEDAYNNTY ACVRTMSALWNLQYCEFDDQ EVFVEVYNLTADPDQITNIA KTIDPELLGKMNYRLMMLQS CSGPTCRTPGVFDPGYRFD |
Post Translational Modifications | The form A (78 kDa) is processed by internal peptidase cleavage to a 32 kDa N-terminal species (form B) and a 48 kDa C-terminal species. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
Protein Name | N-Acetylglucosamine-6-SulfataseGlucosamine-6-SulfataseG6s |
Database Links | Reactome: R-HSA-2022857Reactome: R-HSA-2206305Reactome: R-HSA-432720Reactome: R-HSA-6798695 |
Cellular Localisation | Lysosome |
Alternative Antibody Names | Anti-N-Acetylglucosamine-6-Sulfatase antibodyAnti-Glucosamine-6-Sulfatase antibodyAnti-G6s antibodyAnti-GNS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance