| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GNG7 |
| Gene ID: | 2788 |
| Uniprot ID: | GBG7_HUMAN |
| Immunogen Region: | 1-68 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG7 (NP_443079.1). |
| Immunogen Sequence: | MSATNNIAQARKLVEQLRIE AGIERIKVSKAASDLMSYCE QHARNDPLLVGVPASENPFK DKKPCIIL |
| Tissue Specificity | Expressed in a variety of tissues. Down-regulated in pancreatic and esophageal cancer. |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilization of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum. |
| Protein Name | Guanine Nucleotide-Binding Protein G(I/G(S/G(O Subunit Gamma-7 |
| Database Links | Reactome: R-HSA-1296041 Reactome: R-HSA-163359 Reactome: R-HSA-202040 Reactome: R-HSA-381676 Reactome: R-HSA-392170 Reactome: R-HSA-392451 Reactome: R-HSA-392851 Reactome: R-HSA-400042 Reactome: R-HSA-4086398 Reactome: R-HSA-416476 Reactome: R-HSA-416482 Reactome: R-HSA-418217 Reactome: R-HSA-418555 Reactome: R-HSA-418592 Reactome: R-HSA-418594 Reactome: R-HSA-418597 Reactome: R-HSA-420092 Reactome: R-HSA-428930 Reactome: R-HSA-432040 Reactome: R-HSA-456926 Reactome: R-HSA-500657 Reactome: R-HSA-6814122 Reactome: R-HSA-8964315 Reactome: R-HSA-8964616 Reactome: R-HSA-9009391 Reactome: R-HSA-9634597 Reactome: R-HSA-9660821 Reactome: R-HSA-997272 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Cytoplasmic Side |
| Alternative Antibody Names | Anti-Guanine Nucleotide-Binding Protein G(I/G(S/G(O Subunit Gamma-7 antibody Anti-GNG7 antibody Anti-GNGT7 antibody |
Information sourced from Uniprot.org