Anti-GLYATL2 antibody (84-134 aa) (STJ194514)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human GLYL2 at the amino acid range 84-134
STJ194514
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General Information

Short DescriptionRabbit polyclonal anti-Glycine N-acyltransferase-like protein 2 (84-134 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGLYATL2
Gene ID219970
Uniprot IDGLYL2_HUMAN
ImmunogenSynthesized peptide derived from the human GLYL2 at the amino acid range 84-134
Immunogen Region84-134 aa
SpecificityThis antibody detects endogenous levels of GLYL2 at Human

Additional Info

Post Translational Modifications Acetylation at Lys-19 drastically decreases the production of N-oleoyl and N-arachidonoyl glycines.
Function Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0-CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine.
Protein Name Glycine N-Acyltransferase-Like Protein 2
Acyl-Coa -Glycine N-Acyltransferase-Like Protein 2
Database Links Reactome: R-HSA-177128
Reactome: R-HSA-177135
Reactome: R-HSA-9749641
Cellular Localisation Endoplasmic Reticulum
Alternative Antibody Names Anti-Glycine N-Acyltransferase-Like Protein 2 antibody
Anti-Acyl-Coa -Glycine N-Acyltransferase-Like Protein 2 antibody
Anti-GLYATL2 antibody

Information sourced from Uniprot.org

Citations

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