Host: |
Rabbit |
Applications: |
WB/IHC-P/IF/ICC/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GLDC |
Gene ID: |
2731 |
Uniprot ID: |
GCSP_HUMAN |
Immunogen Region: |
580-749 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 580-749 of human GLDC (NP_000161.2). |
Immunogen Sequence: |
HPFVPLDQAQGYQQLFRELE KDLCELTGYDQVCFQPNSGA QGEYAGLATIRAYLNQKGEG HRTVCLIPKSAHGTNPASAH MAGMKIQPVEVDKYGNIDAV HLKAMVDKHKENLAAIMITY PSTNGVFEENISDVCDLIHQ HGGQVYLDGANMNAQVGICR PGDFGSDVSH |
Function | The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor.CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH). |
Protein Name | Glycine DehydrogenaseDecarboxylating - MitochondrialGlycine Cleavage System P ProteinGlycine DecarboxylaseGlycine DehydrogenaseAminomethyl-Transferring |
Database Links | Reactome: R-HSA-6783984 |
Cellular Localisation | Mitochondrion |
Alternative Antibody Names | Anti-Glycine Dehydrogenase antibodyAnti-Decarboxylating - Mitochondrial antibodyAnti-Glycine Cleavage System P Protein antibodyAnti-Glycine Decarboxylase antibodyAnti-Glycine Dehydrogenase antibodyAnti-Aminomethyl-Transferring antibodyAnti-GLDC antibodyAnti-GCSP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance