Anti-GIRK2 (KCNJ6) antibody [SRM13395] (STJ11108125)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal G Protein-Activated Inward Rectifier Potassium Channel 2 antibody for use in WB, IF, ICC, IF-P and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IF-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM13395 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:1000-1:4000IF/ICC, 1:200-1:800IF-P, 1:200-1:800ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS containing 50% Glycerol and 0.05% BSA, preserved with proclin300 or Sodium Azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KCNJ6 |
| Gene ID | 3763 |
| Uniprot ID | KCNJ6_HUMAN |
| Immunogen | Synthetic peptide. This information is considered to be commercially sensitive. |
| Immunogen Sequence | Human |
Additional Info
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. |
| Protein Name | G Protein-Activated Inward Rectifier Potassium Channel 2Girk-2Bir1Inward Rectifier K(+ Channel Kir3.2Katp-2Potassium Channel - Inwardly Rectifying Subfamily J Member 6 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G Protein-Activated Inward Rectifier Potassium Channel 2 antibodyAnti-Girk-2 antibodyAnti-Bir1 antibodyAnti-Inward Rectifier K(+ Channel Kir3.2 antibodyAnti-Katp-2 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 6 antibodyAnti-KCNJ6 antibodyAnti-GIRK2 antibodyAnti-KATP2 antibodyAnti-KCNJ7 antibody |
Information sourced from Uniprot.org