| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GGT5 (388-587) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GGT5 |
| Gene ID: |
2687 |
| Uniprot ID: |
GGT5_HUMAN |
| Immunogen Region: |
388-587 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 388-587 of human GGT5 (NP_001093251.1). |
| Immunogen Sequence: |
TSHVSVLGEDGSAVAATSTI NTPFGAMVYSPRTGIILNNE LLDLCERCPRGSGTTPSPAV SGDRVGGAPGRCWPPVPGER SPSSMVPSILINKAQGSKLV IGGAGGELIISAVAQAIMSK LWLGFDLRAAIAAPILHVNS KGCVEYEPNFSQEVQRGLQD RGQNQTQRPFFLNVVQAVSQ EGACVYAVSDLRKSGEAAGY |
| Post Translational Modifications | Cleaved by autocatalysis into a large and a small subunit. Glycosylated. |
| Function | Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione-S-conjugate such as leukotriene C4. Does not cleaves gamma-glutamyl compounds such as gamma-glutamyl leucine. May also catalyze a transpeptidation reaction in addition to the hydrolysis reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Acts as a negative regulator of geranylgeranyl glutathione bioactivity by cleaving off its gamma-glutamyl group, playing a role in adaptive immune responses. |
| Protein Name | Glutathione Hydrolase 5 ProenzymeGamma-Glutamyl Transpeptidase-Related EnzymeGgt-RelGamma-Glutamyltransferase 5Ggt 5Gamma-Glutamyltransferase-Like Activity 1Gamma-Glutamyltranspeptidase 5Leukotriene-C4 Hydrolase Cleaved Into - Glutathione Hydrolase 5 Heavy Chain - Glutathione Hydrolase 5 Light Chain |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-2142691Reactome: R-HSA-5423646Reactome: R-HSA-9664535Reactome: R-HSA-9753281 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Glutathione Hydrolase 5 Proenzyme antibodyAnti-Gamma-Glutamyl Transpeptidase-Related Enzyme antibodyAnti-Ggt-Rel antibodyAnti-Gamma-Glutamyltransferase 5 antibodyAnti-Ggt 5 antibodyAnti-Gamma-Glutamyltransferase-Like Activity 1 antibodyAnti-Gamma-Glutamyltranspeptidase 5 antibodyAnti-Leukotriene-C4 Hydrolase Cleaved Into - Glutathione Hydrolase 5 Heavy Chain - Glutathione Hydrolase 5 Light Chain antibodyAnti-GGT5 antibodyAnti-GGTLA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
