Anti-GGH antibody [R38-1R-2] (STJA0035619)

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STJA0035619
€166.88 - €351.88
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-GGH for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R38-1R-2
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Chromatography
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: GGH
Gene ID: 8836
Uniprot ID: GGH_HUMAN
Immunogen: A synthesized peptide derived from human Gamma glutamyl hydrolase
Function Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
Protein Name Gamma-Glutamyl Hydrolase
Conjugase
Gh
Gamma-Glu-X Carboxypeptidase
Database Links Reactome: R-HSA-6798695
Cellular Localisation Secreted
Extracellular Space
Lysosome
Melanosome
While Its Intracellular Location Is Primarily The Lysosome
Most Of The Enzyme Activity Is Secreted
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names Anti-Gamma-Glutamyl Hydrolase antibody
Anti-Conjugase antibody
Anti-Gh antibody
Anti-Gamma-Glu-X Carboxypeptidase antibody
Anti-GGH antibody

Information sourced from Uniprot.org

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