| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GALC |
| Gene ID: | 2581 |
| Uniprot ID: | GALC_HUMAN |
| Immunogen Region: | 40-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GALC (NP_000144.2). |
| Immunogen Sequence: | GGAYVLDDSDGLGREFDGIG AVSGGGATSRLLVNYPEPYR SQILDYLFKPNFGASLHILK VEIGGDGQTTDGTEPSHMHY ALDENYFRGYEWWLMKEAKK RNPNITLIGLPWSFPGWLGK GFDWPYVNLQLTAYYVVTWI VGAKRYHDLDIDYIGIWNER SYNANYIKILRKMLNYQGLQ RVKIIASDNLWESISASMLL DAELFKVVDVIGAHYPGTHS AKDAKLTGKKLWSSEDFST |
| Tissue Specificity | Detected in urine. Detected in testis, brain and placenta (at protein level). Detected in kidney and liver. |
| Function | Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. |
| Protein Name | GalactocerebrosidaseGalceraseGalactocerebroside Beta-GalactosidaseGalactosylceramidaseGalactosylceramide Beta-Galactosidase |
| Database Links | Reactome: R-HSA-9840310 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Galactocerebrosidase antibodyAnti-Galcerase antibodyAnti-Galactocerebroside Beta-Galactosidase antibodyAnti-Galactosylceramidase antibodyAnti-Galactosylceramide Beta-Galactosidase antibodyAnti-GALC antibody |
Information sourced from Uniprot.org