| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GAD1 |
| Gene ID: | 2571 |
| Uniprot ID: | DCE1_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MASSTPSSSATSSNAGADPN TTNLRPTTYDTWCGVAHGCT RKLGLKICGFLQRTNSLEEK SRLVSAFKERQSSKNLLSCE NSDRDARFRRTETDFSNLFA |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GAD67/GAD1 (Q99259). |
| Tissue Specificity | Isoform 1: Expressed in brain. Isoform 3: Expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. |
| Function | Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor. Isoform 3: Enzymatically inactive as glutamate decarboxylase. |
| Protein Name | Glutamate Decarboxylase 167 Kda Glutamic Acid DecarboxylaseGad-67Glutamate Decarboxylase 67 Kda Isoform |
| Database Links | Reactome: R-HSA-888568Reactome: R-HSA-888590Reactome: R-HSA-9022927 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glutamate Decarboxylase 1 antibodyAnti-67 Kda Glutamic Acid Decarboxylase antibodyAnti-Gad-67 antibodyAnti-Glutamate Decarboxylase 67 Kda Isoform antibodyAnti-GAD1 antibodyAnti-GAD antibodyAnti-GAD67 antibody |
Information sourced from Uniprot.org
