| Short Description : | Mouse monoclonal anti-G6PD (35-506aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/WB/ICC/IF |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | AT2F6 |
| Isotype: | IgG2bk |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | By protein-A affinity chromatography |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | G6PD |
| Gene ID: | 2539 |
| Uniprot ID: | G6PD_HUMAN |
| Accession Number: | NP_001035810.1 |
| Immunogen: | Recombinant human G6PD (35-506aa) purified from E. coli |
| Immunogen Region: | 35-506aa |
| Tissue Specificity | Isoform Long is found in lymphoblasts, granulocytes and sperm. |
| Post Translational Modifications | Acetylated by ELP3 at Lys-403.acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403.deacetylation stimulates its enzyme activity. |
| Function | Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. |
| Protein Name | Glucose-6-Phosphate 1-DehydrogenaseG6pd |
| Database Links | Reactome: R-HSA-5628897Reactome: R-HSA-71336Reactome: R-HSA-9818028 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Glucose-6-Phosphate 1-Dehydrogenase antibodyAnti-G6pd antibodyAnti-G6PD antibody |
Information sourced from Uniprot.org
