Western blot analysis of extracts of 293T cells, using G6PC3 antibody (STJ118673) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.

Anti-G6PC3 antibody (4-103) (STJ118673)

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STJ118673
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: G6PC3
Gene ID: 92579
Uniprot ID: G6PC3_HUMAN
Immunogen Region: 4-103
Specificity: A synthetic peptide corresponding to a sequence within amino acids 4-103 of human G6PC3 (NP_612396.1).
Immunogen Sequence: TLGAGIVIAEALQNQLAWLE NVWLWITFLGDPKILFLFYF PAAYYASRRVGIAVLWISLI TEWLNLIFKWFLFGDRPFWW VHESGYYSQAPAQVHQFPSS
Tissue Specificity Ubiquitously expressed. Highly expressed in skeletal muscle, at intermediate levels in heart, brain, placenta, kidney, colon, thymus, spleen and pancreas. Also detected in testis, prostate, ovary, liver, lung, small intestine and peripheral blood lymphocytes.
Function Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function.
Protein Name Glucose-6-Phosphatase 3
G-6-Pase 3
G6pase 3
Glucose-6-Phosphatase Beta
G6pase-Beta
Ubiquitous Glucose-6-Phosphatase Catalytic Subunit-Related Protein
Database Links Reactome: R-HSA-3282872
Reactome: R-HSA-70263
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Glucose-6-Phosphatase 3 antibody
Anti-G-6-Pase 3 antibody
Anti-G6pase 3 antibody
Anti-Glucose-6-Phosphatase Beta antibody
Anti-G6pase-Beta antibody
Anti-Ubiquitous Glucose-6-Phosphatase Catalytic Subunit-Related Protein antibody
Anti-G6PC3 antibody
Anti-UGRP antibody

Information sourced from Uniprot.org

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