Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-G2E3 (1-180) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
G2E3 |
Gene ID: |
55632 |
Uniprot ID: |
G2E3_HUMAN |
Immunogen Region: |
1-180 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human G2E3 (NP_060239.2). |
Immunogen Sequence: |
MNESKPGDSQNLACVFCRKH DDCPNKYGEKKTKEKWNLTV HYYCLLMSSGIWQRGKEEEG VYGFLIEDIRKEVNRASKLK CCVCKKNGASIGCVAPRCKR SYHFPCGLQRECIFQFTGNF ASFCWDHRPVQIITSNNYRE SLPCTICLEFIEPIPSYNIL RSPCCKNAWFHRDCLQVQAI |
Tissue Specificity | Predominantly expressed in brain, liver, kidney, testes and ovary. |
Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death. |
Protein Name | G2/M Phase-Specific E3 Ubiquitin-Protein LigaseG2/M Phase-Specific Hect-Type E3 Ubiquitin Transferase |
Cellular Localisation | NucleusNucleolusCytoplasmShuttles Between The Nucleus And The CytoplasmIn The NucleusDelocalizes From The Nucleolus To The Nucleoplasm In Response To Dna Damage |
Alternative Antibody Names | Anti-G2/M Phase-Specific E3 Ubiquitin-Protein Ligase antibodyAnti-G2/M Phase-Specific Hect-Type E3 Ubiquitin Transferase antibodyAnti-G2E3 antibodyAnti-KIAA1333 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance