Anti-G2E3 antibody (1-180) (STJ116620)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal G2E3 (1-180) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | G2E3 |
| Gene ID | 55632 |
| Uniprot ID | G2E3_HUMAN |
| Immunogen Region | 1-180 |
| Immunogen Sequence | MNESKPGDSQNLACVFCRKH DDCPNKYGEKKTKEKWNLTV HYYCLLMSSGIWQRGKEEEG VYGFLIEDIRKEVNRASKLK CCVCKKNGASIGCVAPRCKR SYHFPCGLQRECIFQFTGNF ASFCWDHRPVQIITSNNYRE SLPCTICLEFIEPIPSYNIL RSPCCKNAWFHRDCLQVQAI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human G2E3 (NP_060239.2). |
Additional Info
| Tissue Specificity | Predominantly expressed in brain, liver, kidney, testes and ovary. |
| Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death. |
| Protein Name | G2/M Phase-Specific E3 Ubiquitin-Protein LigaseG2/M Phase-Specific Hect-Type E3 Ubiquitin Transferase |
| Database Links | |
| Cellular Localisation | NucleusNucleolusCytoplasmShuttles Between The Nucleus And The CytoplasmIn The NucleusDelocalizes From The Nucleolus To The Nucleoplasm In Response To Dna Damage |
| Alternative Antibody Names | Anti-G2/M Phase-Specific E3 Ubiquitin-Protein Ligase antibodyAnti-G2/M Phase-Specific Hect-Type E3 Ubiquitin Transferase antibodyAnti-G2E3 antibodyAnti-KIAA1333 antibody |
Information sourced from Uniprot.org