Anti-FXYD5 antibody (Extracellular region) [M029] (STJA0005425)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenClone (M029) was generated from a proprietary antigen related to the native human FXYD5 protein expressed in A431 epidermoid carcinoma cell line.
General Information
| Short Description | Mouse monoclonal antibody anti-FXYD5/Dysadherin (Extracellular region) is suitable for use in Western Blot, Immunocytochemistry and Immunoprecipitation research applications. |
| Applications | WB/ICC/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | M029 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Antigen Affinity Purified |
| Dilution Range | WB 1:1000ICC 1:100IP 1:100 |
| Formulation | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FXYD5 |
| Gene ID | 53827 |
| Uniprot ID | FXYD5_HUMAN |
| Immunogen | Clone (M029) was generated from a proprietary antigen related to the native human FXYD5 protein expressed in A431 epidermoid carcinoma cell line. |
| Immunogen Region | Extracellular region |
| Specificity | Clone M029 mouse monoclonal antibody detects a 35-55 kDa* band on SDS-PAGE immunoblots of human A431, A549, MeWo, MDA-MB-231 cell, as well as human breast, lung, and skin tissues. The antibody works for western blot, immunoprecipitation, ELISA, and i |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. May increase NKA activity by increasing the apparent affinity for Na(+). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis. |
| Protein Name | Fxyd Domain-Containing Ion Transport Regulator 5Dysadherin |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinBasolateral Cell MembraneIn Kidneys Localizes To The Basolateral Membrane Of The Connecting Tubule |
| Alternative Antibody Names | Anti-Fxyd Domain-Containing Ion Transport Regulator 5 antibodyAnti-Dysadherin antibodyAnti-FXYD5 antibodyAnti-DYSAD antibodyAnti-IWU1 antibodyAnti-HSPC113 antibodyAnti-UNQ2561 antibodyAnti-PRO6241 antibody |
Information sourced from Uniprot.org