| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FUT8 |
| Gene ID: | 2530 |
| Uniprot ID: | FUT8_HUMAN |
| Immunogen Region: | 376-575 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 376-575 of human FUT8 (NP_835367.1). |
| Immunogen Sequence: | FHPIEEYMVHVEEHFQLLAR RMQVDKKRVYLATDDPSLLK EAKTKYPNYEFISDNSISWS AGLHNRYTENSLRGVILDIH FLSQADFLVCTFSSQVCRVA YEIMQTLHPDASANFHSLDD IYYFGGQNAHNQIAIYAHQP RTADEIPMEPGDIIGVAGNH WDGYSKGVNRKLGRTGLYPS YKVREKIETVKYPTYPEAEK |
| Post Translational Modifications | Tyrosine phosphorylated by PKDCC/VLK. |
| Function | Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. |
| Protein Name | Alpha-(1 -6-FucosyltransferaseAlpha1-6fuctFucosyltransferase 8Gdp-L-Fuc -N-Acetyl-Beta-D-Glucosaminide Alpha1 -6-FucosyltransferaseGdp-Fucose--Glycoprotein FucosyltransferaseGlycoprotein 6-Alpha-L-Fucosyltransferase |
| Database Links | Reactome: R-HSA-9694548Reactome: R-HSA-975578 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinMembrane-Bound Form In Trans Cisternae Of Golgi |
| Alternative Antibody Names | Anti-Alpha-(1 -6-Fucosyltransferase antibodyAnti-Alpha1-6fuct antibodyAnti-Fucosyltransferase 8 antibodyAnti-Gdp-L-Fuc -N-Acetyl-Beta-D-Glucosaminide Alpha1 -6-Fucosyltransferase antibodyAnti-Gdp-Fucose--Glycoprotein Fucosyltransferase antibodyAnti-Glycoprotein 6-Alpha-L-Fucosyltransferase antibodyAnti-FUT8 antibody |
Information sourced from Uniprot.org