| Function | Protein O-fucosyltransferase that specifically catalyzes O-fucosylation of serine or threonine residues in EMI domains of target proteins, such as MMRN1, MMRN2 and EMID1. Attaches fucose through an O-glycosidic linkage. O-fucosylation of EMI domain-containing proteins may be required for facilitating protein folding and secretion. Also shows minor alpha-(1,3)-fucosyltransferase activity toward activity toward biantennary N-glycan acceptors. However, this was tested with a library of synthetic substrates and this activity is unsure in vivo. |
| Protein Name | Gdp-Fucose Protein O-Fucosyltransferase 4Alpha-(1 -3-Fucosyltransferase 11Fucosyltransferase XiFuc-TxiFuct-XiGalactoside 3-L-Fucosyltransferase 11Fucosyltransferase 11 |
| Database Links | Reactome: R-HSA-9037629 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Gdp-Fucose Protein O-Fucosyltransferase 4 antibodyAnti-Alpha-(1 -3-Fucosyltransferase 11 antibodyAnti-Fucosyltransferase Xi antibodyAnti-Fuc-Txi antibodyAnti-Fuct-Xi antibodyAnti-Galactoside 3-L-Fucosyltransferase 11 antibodyAnti-Fucosyltransferase 11 antibodyAnti-FUT11 antibodyAnti-POFUT4 antibody |
Information sourced from Uniprot.org
