Anti-FSTL1 antibody (1-308) (STJ118234)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FSTL1 (1-308) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FSTL1 |
| Gene ID | 11167 |
| Uniprot ID | FSTL1_HUMAN |
| Immunogen Region | 1-308 |
| Immunogen Sequence | MWKRWLALALALVAVAWVRA EEELRSKSKICANVFCGAGR ECAVTEKGEPTCLCIEQCKP HKRPVCGSNGKTYLNHCELH RDACLTGSKIQVDYDGHCKE KKSVSPSASPVVCYQSNRDE LRRRIIQWLEAEIIPDGWFS KGSNYSEILDKYFKNFDNGD SRLDSSEFLKFVEQNETAIN ITTYPDQENNKLLRGLCVDA LIELSDENADWKLSFQEFLK CLNPSFNPPEKKCALEDET |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-308 of human FSTL1 (NP_009016.1). |
Additional Info
| Tissue Specificity | Overexpressed in synovial tissues from rheumatoid arthritis. |
| Function | Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors. |
| Protein Name | Follistatin-Related Protein 1Follistatin-Like Protein 1 |
| Database Links | Reactome: R-HSA-201451Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Follistatin-Related Protein 1 antibodyAnti-Follistatin-Like Protein 1 antibodyAnti-FSTL1 antibodyAnti-FRP antibody |
Information sourced from Uniprot.org