• Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°C over night
  • Immunofluorescence analysis of A549 cells, using FPR1 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-FPR1 antibody (151-200 aa) (STJ93134)

SKU:
STJ93134

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-fMet-Leu-Phe receptor (151-200 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FPR1
Gene ID: 2357
Uniprot ID: FPR1_HUMAN
Immunogen Region: 151-200 aa
Specificity: FPR1 Polyclonal Antibody detects endogenous levels of FPR1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human FPR1 at the amino acid range 151-200
Post Translational Modifications Phosphorylated.which is necessary for desensitization.
Function High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis.
Protein Name Fmet-Leu-Phe Receptor
Fmlp Receptor
N-Formyl Peptide Receptor
Fpr
N-Formylpeptide Chemoattractant Receptor
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-444473
Reactome: R-HSA-6783783
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Internalizes In Presence Of Its Ligands
Fmlp
Tafa4 And Ctsg
Alternative Antibody Names Anti-Fmet-Leu-Phe Receptor antibody
Anti-Fmlp Receptor antibody
Anti-N-Formyl Peptide Receptor antibody
Anti-Fpr antibody
Anti-N-Formylpeptide Chemoattractant Receptor antibody
Anti-FPR1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance