| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Fibrillin 2-Mouse (Internal) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000. WB: Not yet tested-our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 314kDa according to NP_034311.1. Therefore we cannot |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Immunogen Region: | Internal |
| Accession Number: | NP_034311.1 |
| Immunogen Sequence: | KELRKLEEHNEDD |
| Function | Fibrillin-2: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. |
| Protein Name | Fibrillin-2 Cleaved Into - Fibrillin-2 C-Terminal Peptide |
| Database Links | Reactome: R-MMU-1474228 Reactome: -MMU-1566948 Reactome: -MMU-2129379 |
| Cellular Localisation | Secreted Extracellular Space Extracellular Matrix |
| Alternative Antibody Names | Anti-Fibrillin-2 Cleaved Into - Fibrillin-2 C-Terminal Peptide antibody Anti-Fbn2 antibody Anti-Fbn-2 antibody |
Information sourced from Uniprot.org