Host: |
Rabbit |
Applications: |
IHC/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Adrenodoxin, mitochondrial (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
FDX1 |
Gene ID: |
2230 |
Uniprot ID: |
ADX_HUMAN |
Immunogen Region: |
N-Term |
Specificity: |
This antibody detects endogenous levels of ADX at Human, Mouse, Rat |
Immunogen: |
Synthesized peptide derived from human N-ternal ADX |
Function | Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. |
Protein Name | Adrenodoxin - MitochondrialAdrenal FerredoxinFerredoxin-1Hepatoredoxin |
Database Links | Reactome: R-HSA-1362409Reactome: R-HSA-196108Reactome: R-HSA-211976Reactome: R-HSA-2395516Reactome: R-HSA-5579026 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-Adrenodoxin - Mitochondrial antibodyAnti-Adrenal Ferredoxin antibodyAnti-Ferredoxin-1 antibodyAnti-Hepatoredoxin antibodyAnti-FDX1 antibodyAnti-ADX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance