Anti-FDX1 antibody (N-Term) (STJA0010365)

SKU:
STJA0010365

Current Stock:
Host: Rabbit
Applications: IHC/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Adrenodoxin, mitochondrial (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FDX1
Gene ID: 2230
Uniprot ID: ADX_HUMAN
Immunogen Region: N-Term
Specificity: This antibody detects endogenous levels of ADX at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human N-ternal ADX
Function Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons.
Protein Name Adrenodoxin - Mitochondrial
Adrenal Ferredoxin
Ferredoxin-1
Hepatoredoxin
Database Links Reactome: R-HSA-1362409
Reactome: R-HSA-196108
Reactome: R-HSA-211976
Reactome: R-HSA-2395516
Reactome: R-HSA-5579026
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Adrenodoxin - Mitochondrial antibody
Anti-Adrenal Ferredoxin antibody
Anti-Ferredoxin-1 antibody
Anti-Hepatoredoxin antibody
Anti-FDX1 antibody
Anti-ADX antibody

Information sourced from Uniprot.org

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