Anti-FDFT1 antibody (150-250) [S4MR] (STJ11102124)

SKU:
STJ11102124
£129.50 - £574.50
Free Shipping
Processing The item has been added

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : S4MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FDFT1
Gene ID: 2222
Uniprot ID: FDFT_HUMAN
Immunogen Region: 150-250
Specificity: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SQS/FDFT1 (P37268).
Immunogen Sequence: MGIGMAEFLDKHVTSEQEWD KYCHYVAGLVGIGLSRLFSA SEFEDPLVGEDTERANSMGL FLQKTNIIRDYLEDQQGGRE FWPQEVWSRYVKKLGDFAKP E
Tissue Specificity Widely expressed.
Function Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway.
Protein Name Squalene Synthase
Sqs
Ss
Fpp -Fpp Farnesyltransferase
Farnesyl-Diphosphate Farnesyltransferase
Farnesyl-Diphosphate Farnesyltransferase 1
Database Links Reactome: R-HSA-191273
Reactome: R-HSA-1989781
Reactome: R-HSA-2426168
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Squalene Synthase antibody
Anti-Sqs antibody
Anti-Ss antibody
Anti-Fpp -Fpp Farnesyltransferase antibody
Anti-Farnesyl-Diphosphate Farnesyltransferase antibody
Anti-Farnesyl-Diphosphate Farnesyltransferase 1 antibody
Anti-FDFT1 antibody

Information sourced from Uniprot.org